Uperio 100mg 28 Tablets

Uperio 100 mg is a cardiovascular medication containing a combination of two active ingredients: Sacubitril (48.6 mg) and Valsartan (51.4 mg). It belongs to a new class of drugs known as Angiotensin Receptor Neprilysin Inhibitors (ARNI). It is primarily used to treat chronic heart failure in adults, particularly those with a reduced ejection fraction.
This combination therapy works through dual mechanisms: Sacubitril inhibits the enzyme neprilysin, which helps increase the levels of beneficial peptides that promote blood vessel dilation and sodium excretion. Valsartan is an angiotensin II receptor blocker (ARB) that prevents the tightening of blood vessels and the release of hormones that can strain the heart. Together, they help the heart pump blood more effectively and reduce the workload on the cardiac muscle.

Key Benefits:
– Advanced Heart Failure Management
– Reduces Cardiovascular Risk.
– Improves Quality of Life
– Dual-Action Formula

CAUTION: This is a prescription-only medication. It must not be taken with an ACE inhibitor; if switching from an ACE inhibitor, a 36-hour washout period is required before starting Uperio to avoid serious swelling (angioedema). Common side effects may include low blood pressure (hypotension), high potassium levels (hyperkalemia), or decreased kidney function.